Massive Ethylene Glycol Ingestion Treated with Fomepizole Alone—A Viable Therapeutic Option
نویسندگان
چکیده
منابع مشابه
Fomepizole for ethylene glycol and methanol poisoning.
n engl j med 360;21 nejm.org may 21, 2009 2216 This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented...
متن کاملThe Role of Hemodialysis and Fomepizole in Ethylene Glycol Intoxication
Ethylene glycol is one of the most common toxic alcohol ingestions requiring hemodialysis for treatment. With the FDA approval in 1997 of fomepizole (4-methylpyrazole), the indications for hemodialysis in addition to fomepizole for ethylene glycol poisoning have been examined in recent articles and case reports. Fomepizole, a competitive inhibitor of alcohol dehydrogenase, binds to the same sit...
متن کاملRole of fomepizole in the management of ethylene glycol toxicity.
OBJECTIVE To systematically review English-language articles on fomepizole administration in patients with ethylene glycol poisoning. DATA SOURCES MEDLINE, EMBASE, Current Contents, and PubMed. Search terms were fomepizole, 4-methylpyrazole, and ethylene glycol. The search was supplemented with a bibliographic review of all relevant articles. STUDY SELECTION All published reports of fomepiz...
متن کاملChildhood methanol ingestion treated with fomepizole and hemodialysis.
Fomepizole (4-methylpyrazole; Antizol) is used increasingly in the treatment of methanol toxicity in adults. Little experience exists with this drug in the pediatric population, however. We present a case of methanol poisoning in a child in whom the use of fomepizole averted intravenous ethanol infusion and the attendant side effects of this therapy.
متن کاملAcute ethylene glycol poisoning after intentional ingestion
Background: We describe a case of acute ethylene glycol poisoning following ingestion of antifreeze agent in which serum ethylene glycol and anion gap were serially measured. Patients: A 66-year old man was hospitalized after intentional ingestion of automotive antifreeze. Upon admission, vital signs, mental status, and neurological functions were normal. Initial laboratory tests revealed no se...
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ژورنال
عنوان ژورنال: Journal of Medical Toxicology
سال: 2010
ISSN: 1556-9039,1937-6995
DOI: 10.1007/s13181-010-0061-2